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Mechanisms of HTLV-I Tax Mediated NF-kB Activation

Edward W Harhaj

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Funding source

National Cancer Institute (NIH)
The goals of this proposal are to: (1) determine the role of the Golgi in the activation of NF-kB by Tax; (2) investigate the mechanisms of NF-kB activation by Tax ubiquitination; and (3) determine how Tax disrupts the function of TAX1BP1.

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