This application requests funds to continue the highly successful Radiation Sciences program at the Stanford University School of Medicine, entitled "Postdoctoral Training In The Radiation Sciences." This training program meets a crucial need in providing training for the next generation of researchers investigating this critical element ofclinical cancer therapy. No other training program at Stanford, and indeed few around the country, addresses the radiation sciences. This program provides our faculty, especially those in non-degree granting departments (e.g., Radiation Oncology and Pathology), the opportunity to recruit and mentor top-notch postdoctoral fellows. The goal of this program is to provide the very best training for its postdoctoral trainees so that they may become successful and independent leaders in the field of radiation and cancer research. The program accomplishes this goal by providing each postdoctoral trainee with a broad and comprehensive curriculum, a vast array of educational resources including seminars, lectures, conferences and workshops specifically geared towards radiation biology, physics, and oncology, a faculty comprised of 16 exceptional preceptors spanning 7 departments with extensive experience in mentoring, and an unparalleled research environment within the Stanford School of Medicine. In addition, postdoctoral trainees audit courses that will aid them in their research and achieving their careergoals. Our postdoctoral trainees become independent scientists. They learn to write grants effectively and to obtain their own individual funding. They also learn extensive professional skills such as lab management and mentoring to more successfully compete in today's job market. A key strength of the program is its true multidisciplinary approach to the radiation sciences incorporating such fields as molecular biology, genetics, cell biology, computational biology and bioinformatics, comparative oncology, developmental biology, and tumor biology, as well as biotechnology development for use in cancer diagnosis and therapeutics.