With this project, scientific evidence will be generated to strengthen the Bolivian CC prevention strategies focused on reducing the incidence of this public health problem in Bolivia, the highest in South America with 36.4 cases per 100,000 women (GLOBOCAN 2008). The distribution of the human papillomavirus of high oncogenic risk (HPV-AR), the lesions caused by HPV-AR and the associated factors in women aged 20-59 years in Chuquisaca, La Paz and Santa Cruz (valley, altiplano and plain) will be estimated; information necessary for the implementation of effective vaccines. There will be scientific and technological support from the Carlos III Health Institute (ISCIII) through the National Microbiology Center (CNM), the National Epidemiology Center (CNE) and the Ramón y Cajal Hospital (HRC). The scientific evidence generated will also contribute to consolidate the current paradigm of integrated management of CC (identify the prevalence of HPV-RA in women with cervical lesions or cancer and treat them in the least number of medical visits). It will allow the Ministry of Health and Sports of Bolivia (MSD) through the National Program of Sexual and Reproductive Health and the Center for Research, Education and Services in Sexual and Reproductive Health (CIES) to have valid tools for designing policies of sexual health care for the prevention of CC. A scientific-university cooperation component is contemplated with the training and transfer of technology to Bolivian personnel who will be able to acquire knowledge and develop skills in laboratory methods and techniques of molecular identification of HPV, liquid cytology and epidemiological research. This with the participation of the ISCIII, the HRC, the Universidad Andina Simón Bolívar (UASB) and the CIES. This proposal promotes synergies among Bolivian institutions and organizations working on this issue: the UASB as an academic and research organization participates as an integrating institution due to its cooperation ties with other institutions, works in permanent collaboration with the San Francisco Xavier University of Chuquisaca (USFX) in research projects in public health especially; The UASB has been working for 10 years with CIES in postgraduate training programs in Sexual and Reproductive Health (SRH). The MSD is the governing entity of the health policies of the country and its priority is the prevention of CC, it has been working for more than 20 years with the UASB, the USFX and more directly with the CIES in the formulation and implementation of health policies in SSR. These institutions will form a multidisciplinary and intersectoral team, from their scope of action will provide their best skills to carry out the project.. This project was identified by RTI International for their own research purposes and some fields do not align with The GO Map categories. End dates were estimated as one year after the start date. The Project Type "Research, Clinical" may not accurately describe this project's focus but was used for all RTI International's Global Noncommunicable Diseases Initiative projects added in June 2018. Specialties were not analyzed. All project funding was valued in 2015 USD.